The Environmental Biostatistics research and training program was established in the Department of Biostatistics in 1971. The training program has had continual financial support over a period of thirty years from the National Institute of Environmental Health Sciences (NIEHS), and it is currently the largest training program funded by NIEHS. This training program has produced many Masters, doctoral, and postdoctoral graduates who now occupy leadership positions in academia, government, and private industry. Faculty and students in this program conduct state-of-the-art biostatistical research relevant to important environmental health problems and provide high-level statistical consulting support for other researchers in the environmental health field. The Department of Biostatistics works closely with the Departments of Environmental Sciences & Engineering and Epidemiology in this research program. The Department also has collaborative research arrangements with researchers at the National Institute of Environmental Health Sciences and the Environmental Protection Agency located at the nearby Research Triangle Park. Environmental health research concentrates on investigating the effects of environmental exposures on human health. The research program also incorporates molecular biology, especially as it relates to gene-environment interactions. Collaboration with the Department of Epidemiology expands the role of Environmental Biostatistics to include statistical issues in genetic epidemiology and reproductive epidemiology. Faculty and students in Environmental Biostatistics also conduct research on toxicology studies in collaboration with researchers in the Department of Environmental Sciences and Engineering.