The Collaborative Studies Coordinating Center (CSCC), a division within the Department of Biostatistics, has been involved with research in cardiovascular disease since its founding in 1971 under the name Lipids Research Clinics (LRC) Coordinating Center. The LRC project was supported by the National Heart, Lung, and Blood Institute (NHLBI), of the National Institutes of Health NIH. The LRC was funded for 19 years, making it one of the longest running studies funded by NIH. The LRC study was actually a collection of studies, including the major clinical trial establishing that cholesterol reduction could prevent heart disease, an epidemiologic cohort study focusing on lipids and cardiovascular disease, and a family study on the genetic factors related to the lipids/cardiovascular disease association. In 1984, the "Lipids Coordinating Center " changed its name to CSCC to reflect the broad area of health research done at the Center. The CSCC is responsible for statistical, scientific, study management, and quality assurance roles for various health research studies, including active development of fieldwork and support for publication activities. The current cardiovascular research projects include: The Arteriosclerosis Risk in Communities Study (ARIC), a cardiovascular epidemiologic study; the Enhancing Recovery in Coronary Heart Diseases Study (ENRICHD), a study of the effect of psychosocial interventions in post-heart attack patients; the Obesity Prevention in Native American Children (PATHWAYS), a school-based intervention to prevent obesity in native American children; the Vitamin Intervention for Stroke Prevention (VISP) study, a randomized clinical trial to prevent recurrent stroke; and the Trial of Activity for Adolescent Girls (TAAG) study, a school-based intervention to prevent a falloff in physical activity as girls move into adolescence.