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Doctors
and other health care professionals are aware that a person's risk of heart
failure increases as body weight goes up. However, they don't need to measure patients'
waists or hips to help reduce the risk for heart failure, according to
researchers from the University of North Carolina at Chapel Hill's Gillings
School of Global Public Health.
Current
procedures, which rely on body mass index tests, are effective predictors of
risk without the additional measurements, according to the UNC study, published
this month in Circulation: Heart Failure, a journal of the American
Heart Association.
 Dr. Laura Loehr "We
were surprised by the results," said lead study author Laura Loehr, MD, PhD, a
2008 graduate of the UNC doctoral program in epidemiology, now a postdoctoral
fellow at the National Institute of Environmental Health Sciences in Research
Triangle Park, N.C., and clinical assistant professor in UNC's department of
medicine.
"We expected waist circumference or waist-to-hip ratio to be a better predictor
of heart failure because excess adiposity (body fat) around the waist is a known
risk factor for diabetes, which is itself an important risk factor for heart
failure. What we found, though, is that the body mass index was an equal
predictor of heart failure, and that's the test most clinicians are using now,
anyway."
Loehr's
research analyzes data collected through the Atherosclerosis Risk in
Communities (ARIC) study, an epidemiologic study of 45- to 65-year-old
residents of four U.S. communities, sponsored by the National Heart Lung and
Blood Institute (NHLBI) and managed by the Collaborative Studies Coordinating
Center at the UNC Gillings School of Global Public Health.
The
current analysis includes nearly 14,600 people followed over 16 years by the
ARIC study. Loehr said the findings were true for both men and women, and for
African Americans and whites, all of whom had greater risk of heart failure if
they were overweight (BMI = 25-29.9) or obese (BMI > 30). The risk
increases with increasing BMI, she said.
Co-authors
of the paper include, from the UNC department of epidemiology, Wayne D.
Rosamond, PhD, professor; Charles Poole, ScD, associate professor; Gerardo
Heiss, MD, PhD, Kenan Distinguished Professor; and Ann Marie McNeill, PhD,
adjunct assistant professor of epidemiology at UNC and associate director of
epidemiology at Merck Research Laboratories, Rahway, N.J.; Patricia P. Chang,
MD, MHS, assistant professor of medicine in the UNC School of Medicine; Lloyd
E. Chambless, PhD, research professor of biostatistics at UNC; and Aaron R.
Folsom, MD, MPH, professor of epidemiology, University of Minnesota School of
Public Health, Minneapolis, Minn.
# # #
An
abstract of the article is available online.
UNC Gillings School of Global Public Health contact: Ramona
DuBose, director of communications,
(919) 966-7467 or ramona_dubose@unc.edu.
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